publications
Selected Publications
Nardou R., Sawyer E., Song Y.J., Wilkinson M., Padovan-Hernandez Y., de Deus J.L., Wright N., Lama C., Faltin S., Goff L.A., Stein-O’Brien G.L., and
Dölen G. Psychedelics reopen the critical period for social reward learning.
Nature 2023.
DOI: 10.1038/s41586-023-06204-3 PDF
Hayes LN, An K, Carloni E, Li F, Vincent E, Trippaers C, Paranjpe M, Dölen G, Goff LA, Ramos A, Kano S, Sawa A. Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry. Nature
2022.
DOI: https://doi.org/10.1038/s41586-022-05274-z.
PDF
Grearson A, Dugan A, Sakmar T, Sivitilli, DM, Gire DH, Caldwell RL, Niell CM,
Dölen G, Wang ZY, Grasse B. The lesser Pacific striped octopus, Octopus chierchiae: an emerging laboratory model for the study of octopuses.
Frontiers in Marine Science
2021.
DOI: 10.3389/fmars.2021.753483 PDF
Lewis E.M, Stein-O'Brien G.L., Patino A.V., Nardou R., Grossman C.D., Brown M., Bangamwabo B., Ndiaye N., Giovinazzo D., Dardani I., Jiang C., Goff L.A., &
Dölen G. Parallel Social Information Processing Circuits
Are Differentially Impacted in Autism.
Neuron. 2020 (in press). doi: 10.1016/j.neuron.2020.10.002. Epub 2020 Oct 27,2020.
PMID: 33113347
PDF
Nardou R, Lewis EM, Rothhaas R, Xu R, Yang A, Boyden E, &
Dölen G. Oxytocin-dependent reopening of a social reward learning critical period with MDMA.
Nature. 2019 May;569(7754):116-120. doi: 10.1038/s41586-019-1075-9. Epub 2019 Apr 3.
PMID: 30944474
PDF
Edsinger, E and
Dölen G. A conserved role for serotonergic neurotransmission in mediating social behavior in octopus.
Current Biology.
2018 October 8; 28: 1–7.
PMID: 30245101
PDF
Dölen G.
Mindreading emerged at least twice in the course of evolution. In Linden, D.J., ed. Think Tank: Forty Curious Neuroscientists Explain the Biological Roots of Human Experience.
Yale University Press
(April 2018).
ISBN: 9780300225549. Library (Worldcat.org) Amazon.
PDF
Hung LW, Neuner S, Polepalli JS, Beier K, Wright M, Walsh J, Lewis E,
Luo L, Deisseroth K , Dölen G, Malenka, RC. Gating of social reward by oxytocin in the ventral tegmental area. Science.
2017 Sep 29;357(6358):1406-1411. PMID: 28963257
PDF
Dölen G, Setting the mood for love. Nature Neuroscience. 2017 Feb 23;20(3):379-380. PMID: 28230842
PDF
Dölen G, and Sahin M Editorial: Essential Pathways and Circuits of Autism Pathogenesis.2016 Apr 26;10:182. Frontiers in Neuroscience.
PMCID: PMC4844597 PDF
Lammel S,Dölen G,and Malenka RC. Optogenetic Approaches to Neural Circuit Analysis in the Mammalian Brain. In Lehner T, Miller BL, and State MW, eds. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. Elsevier, Inc. 2016. ISBN: 9780128001059
Dölen G, Autism: oxytocin, serotonin, and social reward.Social Neuroscience.
2015 Aug 28. PMID: 26317636
PDF
Dölen G,
Malenka RC, Perlumutter JS, Brose N, Frackowiak R, Cuthbert BN, Diester I, Mansuy I, Kroker, KS, Boekers TM, Pascual-Leone A, Feng G. Pathophysiological Toolkit: Genes to Circuits. In Nikolich, K. and S. E. Hyman, eds.
Translational Neuroscience: Toward New Therapies.
Strüngmann Forum
Reports, vol. 17, J. Lupp, series editor. Cambridge, MA:
MIT Press, 2015. ISBN: 9780262029865. PDF
Diester I, Hefti F, Mansuy I,
Pascual-Leone A, Robbins TW, Rubin LL,
Sawa A, Wernig M,
Dölen G,
Hyman SE,
Mucke L, Nikolich K, and Sommer B. Bridging the Gap between Patients and Models.
In Nikolich, K. and S. E. Hyman, eds.
Translational Neuroscience: Toward New Therapies.
Strüngmann Forum
Reports, vol. 17, J. Lupp, series editor. Cambridge, MA:
MIT Press, 2015. ISBN: 9780262029865.
PDF
Dölen G.Oxytocin: parallel processing in the social brain?Journal of Neuroendocrinology.2015 Jun;27(6):516-35.
PMID: 25912257 PDF
Dölen G. SFARI: Cross Talk.
https://spectrumnews.org/opinion/cross-talk/cross-talk-how-do-we-fix-the-broken-postdoc-pipeline/ PDF
Dölen G, Darvishzadeh A, Huang KW, Malenka, RC. Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin. Nature
2013 Sep 12;501(7466):179-84.
PMID: 24025838
PDF
Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dölen G, Bader PL, Grueter BA, Goold C, Fisher E, Clifford K, Rengarajan P, Kalikhman D, Loureiro D, Saw NL, Zhengqui Z, Miller MA, Lerch JP, Henkelman RM, Shamloo M, Malenka RC, Crawley JN, and Dolmetsch RE. Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome. Cell Rep.
2014 May 22;7(4):1077-92. PMID: 24794428
PDF
Bhakar AL, Dölen G, Bear MF. The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci. 2012;35:417-43. PMID: 22483044
PDF
Dölen G, Carpenter RL, Ocain TD, Bear MF. Mechanism-based approaches to trating fragile X. Pharmacol Ther.
2010 Jul;127(1):78-93. PMID: 20303363 PDF
Dölen G, Bear MF. Fragile X syndrome and autism: from disease model to therapeutic targets. J Neurodev Disord.
2009 Jun;1(2):133-40 PMID: 21547712
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Dölen G, Bear MF. Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome. J Physiol.
2008 Mar 15;586(6):1503-8. PMID: 18202092
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Bear MF, Dölen G, Osterweil E, Nagarajan N. Fragile X: translation in action. Neuropsychopharmacology. 2008 Jan;33(1):84-7. PMID: 17940551
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Dölen G. Genetic interaction between Fmr1 and Grm5: A role for mGluR5 in the pathogenesis of Fragile X Syndrome. (2008). Thesis-Ph.D.-- Brown University. PDF
Dölen G, Osterweil E, Rao BS, Smith GB, Auerbach BD, Chattarji S, Bear MF. Correction of fragile X syndrome in mice. Neuron. 2007 Dec 20;56(6):955-62. PMID: 18093519 PDF
Herrera E, Brown L, Aruga J, Rachel RA, Dölen G, Mikoshiba K, Brown S, Mason CA. Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell.
2003 Sep 5;114(5):545-57. PMID: 13678579 PDF
Rachel RA, Dölen G, Hayes NL, Lu A, Erskine L, Nowakowski RS, Mason CA. Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina. J Neurosci.
2002 Jun 1;22(11):4249-63. PMID: 12040030 PDF
Dölen, G. The Development of mind: perspectives from Autistic disorder. (1997). Unpublished coursework- A.B.-- Duke University. PDF